MSE™ (Multiple Stabilized Enzymes) is
our major digestive enzyme product sold. It is mostly sold as a dry powder in sealed 5 gallon
pails to be used in livestock feeds. MSE contains various enzymes including:
Also included in MSE are
numerous strains of yeast, fungi and bacteria. In addition MSE contains crucial
vitamins and minerals, as well as detoxifiers.
major advantage of using MSE is to increase the digestibility of feeds. MSE can
increase the digestibility by 8-10% in ruminants and 12-14% in monogastrics.
This means swine can gain the, same amount on 12-14% less feed. This increase in
digestibility also means the release and usage of vitamins and minerals that
would normally pass through the animal. With less waste being produced, there is
consequently less manure and less undegrated material in that manure. That means
The bacteria, fungi and yeast included in MSE also provides
your animal with a probiotics source. Probiotics (now termed DFM’s) are
beneficial in increasing digestion factors and acting as a safe-guard during
times of stress. The following article gives an explanation on the importance of
DFM’s and compares them to antibiotics.
With the widespread availability
of antibiotics over forty years ago, antibiotic feeding became a common practice
for use as a therapeutic agent and a growth stimulant for livestock. Since their
introduction, however, there has been a growing concern about the use of
antibiotics resulting in the development of resistant strains of bacteria, which
made subsequent use of antibiotics less effective. This later resulted in the
banning of most antibiotics as growth promoters in animal feed supplements.
There has also been much public concern over the use of antibiotics, due to the
possibility of a residue left in meat. Today, only the disease preventive
antibiotics are allowed and they are widely used for this purpose.
oral antibiotics have been shown to cause intestinal upsets after ingestion,
despite their effectiveness for curing the disease for which they have been
prescribed. These intestinal upsets are usually caused by the disruption and
death of the beneficial bacterial flora, as a result of the antibiotic.
Therefore, full recovery is slowed or even prevented with disease treatment by
These factors have led to the search for alternatives to
feeding antibiotics. Probiotics are being considered to fill this role, and many
producers are already using them in preference to antibiotics. The word
“probiotic” has come to have an elusive meaning. One satisfactory definition is,
“a living microbial feed supplement which beneficially affects the host animal
by improving its intestinal microbial balance.” In 1989, however, the FDA
required manufacturers to use the term direct-fed microbial (DFM) rather than
probiotic. The FDA defines DFM as “a source of live (viable) naturally-occurring
microorganisms.” This definition includes bacteria, fungi, and yeast.
entire mode of action of DFM’s is not wholly known. It’s general effects,
however, are simple – especially when compared to antibiotics. Antibiotics
function via the destruction of pathogenic organisms in an animal’s digestive
system. In other words, an antibiotic kills microbial life in the G. 1. tract in
an effort to destroy pathogens. The problem with this is that many of the
beneficial microorganisms are killed in addition to pathogenic organisms. This
can be very detrimental since the beneficial microorganisms are the animals
principal defence mechanisms against pathogens, as well as being important in
the digestive process. This loss of these microbes creates a stress factor on
the animal and slows recovery until these beneficial microorganisms regain their
On the other hand, direct-fed microbials actually add live
(viable), beneficial organisms to an animal’s system. These organisms increase
the health of an animal’s system in several different ways. To develop an
understanding, one should know the purpose of the gut microflora (digestive
tract microorganisms). Digestive tract microflora aid the animal in digesting
feed and aid to resist infections naturally by competing with and fighting
against pathogens while serving to protect the G. 1. tract walls. This is shown
best by the fact that germ-free animals are more susceptible to disease than are
normal animals with a complete intestinal microflora. For example, whereas a
germ-free mouse can be killed with 10 cells of Salmonella enteritidis, 1,000,000
cells are required to kill a conventional mouse. Taking this into consideration,
one can easily see the risk of recovery from a mostly absent microflora due to
the feeding of an antibiotic, since an antibiotic tries to remove pathogens
instead of naturally increasing the animals health and resistance to these
Using the aforementioned information, it is evident that the
presence of microflora greatly decreases an animal’s chance of getting sick; but
why is this so? Some possible modes of action of DFM’s include:
1.Suppression of infectants by:
a. production of antibacterial compounds
b. competition for nutrients
c. competition for adhesion sites
2. Alteration of microbial metabolism by:
a. increased enzyme
b. decreased enzyme activity3. Stimulation of immunity
a. increased antibody levels
b. increased macrophage activity
Besides the factors mentioned that generally increase the state of health of an
animal, DFM’s have been shown to affect many other aspects such as passage rate,
digestibility, rate of gain, milk production, etc….
feeding, DFM’s have been shown to maintain herd health without the side effects
that are present when using antibiotics. A feeding program involving a continual
supply of DFM’s to an animal results in a stronger and healthier gut microflora.
This yields an animal that is less susceptible to illness and disease. Also, if
the treatment of an animal with a DFM is plausible, there are fewer or no side
effects as compared to an antibiotic. In addition, Aspergillus oryzae (A.O.) and
Sacharomyces cerevisiae (S.C.) cultures have been shown to increase fiber
digestion and milk yield. Other possible benefits include increased rate of
passage, rate of fermentation, DM digestibility, CP digestibility, ADG and total
VFA production. Decreases include a lower feed: grain ratio and less methane
production. Use of other microbials and microbial by-products, such as bacteria
and enzymes, can aid in the digestive process even further. When it is necessary
to treat an animal with an antibiotic, DFM’s are especially beneficial as an aid
to reduce stress and boost the animal’s microflora population back to normal for
a speedy recovery.
This is where
Natur’sWay MSE enzyme feed additive
comes into play. In addition to the multiple enzymes included for increased feed
conversion, MSE also contains more active microbials than many DFM products.
These microbials include multiple strains of bacteria, yeast and fungi.
Therefore, MSE is not intended to merely increase digestibility, but it also
adds crucial microbes (DFM’S) to stabilize and increase the health of the G. I.
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